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Somatic mutations in chromatin remodeler genes could modify the epigenomic landscape of CLL, but These are uncommon Within this malignancy compared to other lymphoid neoplasms. CHD2 is mutated in five% of CLL and seven% of MBL.seventy five The histone methyltransferase SETD2 and ARID1A may also be mutated in a little proportion of patients. Of Be a